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Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
(Q)SAR
Adequacy of study:
key study
Study period:
06/12/2017-20/12/2017
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model, but not (completely) falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
QSAR value. The substance falls within the applicability domain of the model and was therefore reliably predicted for its acute toxicity (48h-EC50) to daphnid. Therefore, this endpoint value can be considered valid for use in risk assessment and classification and labelling.
Guideline:
other: REACH Guidance on QSARs R.6 (following OCDE 202, EU C.2)
Principles of method if other than guideline:
Not required
GLP compliance:
not specified
Specific details on test material used for the study:
Smile : C=CCCCCCCCCC(=O)[O-].[Na+]
Analytical monitoring:
not required
Details on sampling:
Not applicable
Vehicle:
not specified
Details on test solutions:
Not applicable
Test organisms (species):
Daphnia sp.
Details on test organisms:
Not applicable
Test type:
other: Not applicable
Water media type:
other: Not applicable
Limit test:
no
Total exposure duration:
48 h
Remarks on exposure duration:
Not applicable
Post exposure observation period:
Not applicable
Hardness:
Not applicable
Test temperature:
Not applicable
pH:
Not applicable
Dissolved oxygen:
Not applicable
Salinity:
Not applicable
Conductivity:
Not applicable
Nominal and measured concentrations:
Not applicable
Details on test conditions:
Not applicable
Key result
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
ca. 39 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility
Remarks on result:
other: QSAR predicted value
Details on results:
Not applicable
Results with reference substance (positive control):
Not applicable
Reported statistics and error estimates:
95% confidence limits (α = 0.05): 19 – 77 mg/L
Validity criteria fulfilled:
yes
Executive summary:

The 48h-EC50 of undec-10-enoic acid to daphnids was predicted as 39 mg/L (19 – 77 mg/L)

Description of key information

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
39 mg/L

Additional information