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EC number: 240-166-3 | CAS number: 16026-16-7
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 6th February - 15th May 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: isothermal thermogravimetry
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: SOAP005-2
- Expiration date of the lot/batch: 15 October 2022
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: Ambient, stored under nitrogen in a desiccator
TREATMENT OF TEST MATERIAL PRIOR TO TESTING
- Treatment of test material prior to testing: Following receipt of the test item, it was found that the material readily absorbed moisture in the parent container. Consequently, on advice from the Sponsor, a sub-sample was dried overnight at 100°C and then stored in a desiccator under a headspace of nitrogen. - Temp.:
- 25 °C
- Vapour pressure:
- 0.6 Pa
- Conclusions:
- The vapour pressure of the test item is 0.6 Pa at 25°C.
- Executive summary:
A study to determine the vapour pressure of the test item was conducted according to the OECD 104 guideline (Dunning 2018). The vapour pressure was determined by the effusion method using isothermal thermogravimetry analysis.
The vapour pressure of the test item was determined to be 0.6 Pa at 25°C.
The study is GLP-compliant and was conducted according to the standard guideline, therefore is considered reliable without restrictions and suitable as a key study for this endpoint.
Reference
A summary of results is shown below:
Parameter |
Run 1 |
Run 2 |
|
|
|
Correlation (R2) |
0.9325 |
0.9312 |
Slope |
-1034 |
-2604 |
Intercept |
3.459 |
8.194 |
log10PTat 25°C |
-0.0081 |
-0.54 |
PT(Pa) at 25°C |
0.98 |
0.29 |
|
|
|
Description of key information
The vapour pressure of the test item is 0.6 Pa at 25°C.
Key value for chemical safety assessment
- Vapour pressure:
- 0.6 Pa
- at the temperature of:
- 25 °C
Additional information
A study to determine the vapour pressure of the test item was conducted according to the OECD 104 guideline (Dunning 2018). The vapour pressure test was conducted by the effusion method using isothermal thermogravimetry analysis.
The vapour pressure of the substance was determined to be 0.6 Pa at 25°C.
The study is GLP-compliant and was conducted according to the standard guideline, therefore is considered reliable without restrictions and suitable as a key study for this endpoint.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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