Registration Dossier
Registration Dossier
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EC number: 611-821-4 | CAS number: 5934-29-2
Endpoint summary
Administrative data
Key value for chemical safety assessment
Genetic toxicity in vitro
Description of key information
Moreover, the genotoxic/mutagenic potential of L-histidine can be excluded for various reasons. L-histidine is a naturally occuring essential amino acid and a normal constituent in living cells. It is ingested daily in significant amounts and a basic metabolite and building block of all living organisms. Aditionally, L-histidine was shown not be a carcinogen (Ikezaki, 1996).
Additional information
Justification for classification or non-classification
Moreover, the genotoxic/mutagenic potential of L-histidine can be excluded for various reasons. L-histidine is a naturally occuring essential amino acid and a normal constituent in living cells. It is ingested daily in significant amounts and a basic metabolite and building block of all living organisms. Aditionally, L-histidine was shown not be a carcinogen (Ikezaki, 1996).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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