Registration Dossier
Registration Dossier
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EC number: 231-672-5 | CAS number: 7681-55-2
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- in vitro gene mutation study in bacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- not specified
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- publication
- Title:
- Final Report on the Safety Assessment of Sodium Iodate
- Author:
- Cosmetic Ingredient Review (Expert Panel)
- Year:
- 1 995
- Bibliographic source:
- Journal of the American College of Toxicology 14(3):231-239, Raven Press, Ltd., New York
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- An Ames test was conducted with the substance
- GLP compliance:
- not specified
- Type of assay:
- bacterial reverse mutation assay
Test material
- Reference substance name:
- Sodium iodate
- EC Number:
- 231-672-5
- EC Name:
- Sodium iodate
- Cas Number:
- 7681-55-2
- Molecular formula:
- HIO3.Na
- IUPAC Name:
- sodium iodate
Constituent 1
Results and discussion
Test results
- Key result
- Species / strain:
- not specified
- Metabolic activation:
- not specified
- Genotoxicity:
- negative
- Cytotoxicity / choice of top concentrations:
- not specified
- Vehicle controls validity:
- not specified
- Untreated negative controls validity:
- not specified
- Positive controls validity:
- not specified
Applicant's summary and conclusion
- Conclusions:
- The test material showed no mutagenic activity by the Ames test.
- Executive summary:
The test material showed no mutagenic activity by the Ames test.
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