Registration Dossier
Registration Dossier
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EC number: 269-225-1 | CAS number: 68201-55-8
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- other: summary of experimental results
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- abstract
- Remarks:
- summary of experimental results, citing i.a. the available OECD 404 and 405 study, but original study report of the present information is not available
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 1 983
- Report date:
- 1983
Materials and methods
- Principles of method if other than guideline:
- The acute oral LD50 was determined in rats.
- GLP compliance:
- no
Test material
- Reference substance name:
- Betaines, coco alkyldimethyl(3-sulfopropyl)
- EC Number:
- 269-225-1
- EC Name:
- Betaines, coco alkyldimethyl(3-sulfopropyl)
- Cas Number:
- 68201-55-8
- Molecular formula:
- C7H17NO3S·[CH2]6-16
- IUPAC Name:
- [3-(dodecyldimethylazaniumyl)propyl]trioxo-λ⁶-sulfanuide
- Reference substance name:
- Water
- EC Number:
- 231-791-2
- EC Name:
- Water
- Cas Number:
- 7732-18-5
- Molecular formula:
- H2O
- IUPAC Name:
- Water
Constituent 1
Constituent 2
Test animals
- Species:
- rat
Administration / exposure
- Route of administration:
- oral: unspecified
Results and discussion
Effect levelsopen allclose all
- Dose descriptor:
- LD50
- Effect level:
- 6.4 mL/kg bw
- Based on:
- test mat.
- Dose descriptor:
- LD50
- Effect level:
- ca. 3 200 mg/kg bw
- Based on:
- act. ingr.
- Remarks:
- recalculated from the 50% aqueous solution
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- The acute LD50 oral was determined to be 6.4 ml/kg in rats for a 50% solution of the registered substance, which corresponds to a LD50 oral of ca. 3.2 g/kg. So the substance does not need to be classified as acutely toxic via the oral route.
- Executive summary:
The acute LD50 oral was determined to be 6.4 ml/kg in rats for a 50% solution of the registered substance, i.e. LD50 = ca. 3.2 g/kg, no classification as acutely toxic is triggered.
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