Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 246-874-9 | CAS number: 25340-17-4
Endpoint summary
Administrative data
Description of key information
Skin: Irritating
Eye: Not irritating
Based on tests with rabbits DEB mixed isomers has demonstrated a range of potential for skin irritation, from mild and reversible to severely irritating. DEB mixed isomers causes mild irritation when instilled directly into the eyes of rabbits. However the eye irritation was not severe and fully resolved within the 7 day observation perio
Based on tests with rabbits DEB mixed isomers has demonstrated a range of potential for skin irritation, from mild and reversible to severely irritating. DEB mixed isomers causes mild irritation when instilled directly into the eyes of rabbits. However the eye irritation was not severe and fully resolved within the 7 day observiod.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
Based on tests with rabbits DEB mixed isomers has demonstrated a range
of potential for skin irritation, from mild and reversible to severely
irritating. DEB mixed isomers causes mild irritation when instilled
directly into the eyes of rabbits. However the eye irritation was not
severe and fully resolved within the 7 day observation period.
Justification for classification or non-classification
Classification as Irritating to the skin Category 2 according to CLP; R38 according to DSD is required.
No classification for eye irritation is necessary
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
