Registration Dossier
Registration Dossier
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EC number: 208-161-0 | CAS number: 513-42-8
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Remarks:
- ToxPlanet Research
Data source
Reference
- Reference Type:
- secondary source
- Title:
- ToxPlanet Research
- Author:
- ERM
- Year:
- 2 017
Materials and methods
In vitro test system
- Source species:
- rabbit
Test animals
- Species:
- rabbit
Results and discussion
In vivo
Results
- Irritation parameter:
- other: administration on to skin (rabbit)
- Remarks on result:
- probability of moderate irritation
- Irritant / corrosive response data:
- LDLo: 2 gm/kg (administration onto the skin, rabbit) :
500 mg dose, moderate irr effects (administration onto the skin, rabbit)
Applicant's summary and conclusion
- Interpretation of results:
- Category 2 (irritant) based on GHS criteria
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