Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Remarks:
GESTIS information
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Remarks:
GESTIS remark on dermal toxicity

Data source

Materials and methods

Test animals

Species:
rabbit

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LDLo
Effect level:
2 000 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
Category 2 based on GHS criteria
Conclusions:
Hinsichtlich der Hautresorbierbarkeit gibt ein dermaler Toxizitätswert (LDLo Kaninchen: 2000 mg/kg KG) lediglich den Hinweis, dass eine dermale Aufnahme akut toxisch wirkender Dosen über die Haut prinzipiell möglich ist.
In Analogie zum Allylalkohol ist sicherheitshalber davon auszugehen, dass Flüssigkeitskontakt einen wesentlichen Beitrag zur Gesamtexposition am Arbeitsplatz leisten kann