Registration Dossier
Registration Dossier
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EC number: 202-809-6 | CAS number: 100-00-5
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Repeated dose toxicity: via oral route - systemic effects
Endpoint conclusion
- Dose descriptor:
- LOAEL
- 3 mg/kg bw/day
Repeated dose toxicity: inhalation - systemic effects
Endpoint conclusion
- Dose descriptor:
- LOAEC
- 9.81 mg/m³
Additional information
Repeated dose toxicity: inhalation - systemic effects (target organ) cardiovascular / hematological: other
Justification for classification or non-classification
The LOAEC for effects on red blood cells (MetHb formation, haemosiderosis) is 9.81 mg/m³, similar effects were seen after oral dosing at 3 mg/kg bw/day. This justifies classification as STOT RE Cat 1. However, the existing legal classification deviates from this finding and is given in Section 2.
Under DSD, T-R48/23/25 is the appropriate classification based on the available data. However, the existing legal classification is deviant from this finding and is given in Section 2.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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