Registration Dossier
Registration Dossier
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EC number: 210-459-0 | CAS number: 616-02-4
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- no data
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Limited publication
Data source
Reference
- Reference Type:
- publication
- Title:
- The place of the range-finding test in the industrial toxicology laboratory.
- Author:
- Smyth, H.F. Jr., Carpenter, C.P.
- Year:
- 1 944
- Bibliographic source:
- J IND HYG 26:269-273, 1944.
Materials and methods
- Principles of method if other than guideline:
- no information
Test material
- Reference substance name:
- Citraconic anhydride
- EC Number:
- 210-459-0
- EC Name:
- Citraconic anhydride
- Cas Number:
- 616-02-4
- Molecular formula:
- C5H4O3
- IUPAC Name:
- 3-methyl-2,5-dihydrofuran-2,5-dione
- Details on test material:
- citraconic anhydride
Constituent 1
Test animals
- Species:
- rabbit
Results and discussion
Applicant's summary and conclusion
- Interpretation of results:
- Category 1 (corrosive)
- Remarks:
- Criteria used for interpretation of results: expert judgment
- Conclusions:
- Citraconic acid anhydride tested full strength by application of 0.01ml of undiluted sample to an area upon the clipped belly of an albino rabbit caused severe injury like that caused by morpholine (no further data).
- Executive summary:
Citraconic acid anhydride tested full strength by application of 0.01ml of undiluted sample to an area upon the clipped belly of an albino rabbit caused severe injury like that caused by morpholine (no further data).
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