Registration Dossier
Registration Dossier
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EC number: 270-659-9 | CAS number: 68475-76-3 A complex combination of finely divided inorganic particles separated from the exit gases formed during the manufacture of Portland cement. The flue dust consists of uncalcined raw materials along with partially calcined materials. Some Portland cement clinker is usually included. The major constituents of kiln dust are calcium carbonate, clays, shales, quartz and sulfate salts. The following materials may also be present:@Dolomite@Ca(OH)2@Feldspars@CaSO4@Fly ash@KCl@Iron oxides@K2CO3@CaF2@K2SO4@CaO@Na2SO4@Glasses of SiO2, Al.s@Portland cement chemicals [659
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Effect on fertility: via oral route
- Dose descriptor:
- NOAEL
- 1 010 mg/kg bw/day
Additional information
Oral route:
No toxicity according to the result of a reproduction/development toxicity screening test..
Dermal route:
The dermal exposure route has no significance. First, intake of the inorganic constituents of Flue Dust over the skin is nearly inpossible. Second, dermal exposure will end in skin irritation. Therefore workers and consumers are informed to wear skin protection (gloves, adequate clothes).
Inhalation route:
Flue Dust is a dusty material, but only about 10 m-% of the substance is respirable. Most of the inhalable dust will therefore end in nose, mouth, throat or the upper respiratory tract. From there, the substance can reach the inner organs.
Therefore it was concluded, that for this endpoint the oral exposure route is most appropriate.
Short description of key information:
Flue Dust shows no toxicity on reproduction and fertility, based on the study results of a Klimisch 1 study, where no effect was observed on the reproduction and fertility of the test animals.
Effects on developmental toxicity
Description of key information
Flue Dust is not teratogenic. Based on the study results of a Klimisch 1 study, no effect was observed on the prenatal development of the test animals.
Effect on developmental toxicity: via oral route
- Dose descriptor:
- NOAEL
- 1 010 mg/kg bw/day
Additional information
The dermal exposure route has no significance. First, intake of the inorganic constituents of Flue Dust over the skin is nearly inpossible. Second, dermal exposure will end in skin irritation. Therefore workers and consumers are informed to wear skin protection (gloves, adequate clothes).
Flue Dust is a dusty material, but only about 10 m-% of the substance is respirable. Most of the inhalable dust will therefore end in nose, mouth, throat or the upper respiratory tract. From there, the substance can reach the inner organs.
Therefore it was concluded, that for this endpoint the oral exposure route is most important.
Justification for classification or non-classification
There is no human evidence that Flue Dust is toxic to reproduction. Additionally, the study result of a Klimisch 1 study shows no toxicity to reproduction for Flue Dust. Therefore a classification for toxicity to reproduction is not warranted.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
