Registration Dossier
Registration Dossier
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EC number: 231-157-5 | CAS number: 7440-47-3
Health surveillance data
Administrative data
- Endpoint:
- health surveillance data
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable, well documented review on occupational exposure data.
Cross-reference
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- other: evaluation
- Title:
- Toxicological profile of chromium
- Author:
- ATSDR
- Year:
- 2 000
- Bibliographic source:
- Atlanta U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry (ATSDR). September 2000
Materials and methods
- Study type:
- other: all available data summarized
- Endpoint addressed:
- skin irritation / corrosion
- eye irritation
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- All available stuidies on health effects of chromium summarized.
- GLP compliance:
- no
Test material
- Reference substance name:
- various chromium(3+) containing substances
- IUPAC Name:
- various chromium(3+) containing substances
Constituent 1
Method
- Type of population:
- occupational
- Ethical approval:
- not applicable
Results and discussion
- Results:
- An extensive review of chromium health effects indicates that no skin or eye irritation has been reported due to occupational exposure to chromium metal, chromium(III) oxide or ferrochromium.
Applicant's summary and conclusion
- Conclusions:
- Bases on this extensive review, there are no reports available on skin or eye irritation caused by chromium metal, chromium(III) oxide or ferrochromium.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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