Ethylene di(acetate)

Ecotoxicological Summary

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:

PNEC aqua (freshwater)

PNEC value:

0.04 mg/L

Assessment factor:

1 000

Extrapolation method:

assessment factor

PNEC freshwater (intermittent releases):

0.405 mg/L

Marine water

Hazard assessment conclusion:

PNEC aqua (marine water)

PNEC value:

0.004 mg/L

Assessment factor:

10 000

Extrapolation method:

assessment factor

STP

Hazard assessment conclusion:

PNEC STP

PNEC value:

10 mg/L

Assessment factor:

10

Extrapolation method:

assessment factor

Sediment (freshwater)

Hazard assessment conclusion:

PNEC sediment (freshwater)

PNEC value:

0.174 mg/kg sediment dw

Extrapolation method:

equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:

PNEC sediment (marine water)

PNEC value:

0.017 mg/kg sediment dw

Extrapolation method:

equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:

no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:

PNEC soil

PNEC value:

0.019 mg/kg soil dw

Extrapolation method:

equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:

no potential for bioaccumulation

Conclusion on classification

According to Article 13 of Regulation (EC) No. 1907/2006 "General Requirements for Generation of Information on Intrinsic Properties of substances", Information on intrinsic properties of substances may be generated by means other than tests e.g. from information from structurally related substances (grouping or read-across), provided that conditions set out in Annex XI are met. Annex XI, "General rules for adaptation of this standard testing regime set out in Annexes VII to X” states that “substances whose physicochemical, toxicological and ecotoxicological properties are likely to be similar or follow a regular pattern as a result of structural similarity may be considered as a group, or ‘category’ of substances. This avoids the need to test every substance for every endpoint”. Since the analogue concept is applied to the target substanceethylene diacetate (CAS 111-55-7), data will be generated from a representative read-across substances to avoid unnecessary animal testing. Additionally, once the analogue concept is applied, substances will be classified and labelled on this basis.

 

Degradation

Biodegradation: readily biodegradable (60% after 28 d; no 10-day window required (OECD 301C) (read-across)

Bioaccumulation

Low potential for bioaccumulation: Log Kow: 0.1 (OECD 117)

Acute aquatic toxicity

96 h, LC50 (Pimephales promelas): 40.45 m/L (measured)

48 h, EC50 (Daphnia magna): > 116.3 mg/L (measured)

72 h, ErC50 (Selenastrum capricornutum): > 119.86 mg/L(measured)

Chronic aquatic toxicity

72 h, NOErC (Selenastrum capricornutum): ≥ 119.86 mg/L (measured)

Non-classification according to CLP

Based on the data listed above, ethylene diacetate is considered to be rapidly degradable and has a low potential for bioaccumulation. The acute and chronic effect concentrations (L(E)C50, NOErC) are all > 1 mg/L for fish, aquatic invertebrates and algae.

Therefore, the substance is not classified and labelled for environmental hazards according to the consolidated version of Regulation (EC) No 1272/2008 and further amendments (ATPs).

Non-classification according to DSD/DPD

Based on the data above, ethylene diacetate is considered to be rapidly degradable and has low potential for bioaccumulation. The acute aquatic toxicity L(E)C50 values are all > 1 mg/L for fish, aquatic invertebrates and algae. Thus, ethylene diacetate does not need to be classified and labeled as environmental hazard according to Directive 67/548/EEC.