Registration Dossier
Registration Dossier
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EC number: 402-070-1 | CAS number: 88122-99-0 UVINUL T 150
Endpoint summary
Administrative data
Description of key information
The substance did not cause skin irritation/corrosion in the animals tested. An eye irritation test demonstrated that slight (but not significant) eye irritation was seen following instillation of the substance in the eye. As these effects occurred in only at 24 hours in 1/3 test animals and were fully reversible the substance is hence classified as non-irritating. There are no data for respiratory irritation, the weight of evidence would suggest that respiratory irritation is unlikely to occur.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
Skin irritation
A GLP compliant study (OECD 404) was conducted to determine the skin irritation/corrosion potential of the substance. The substance did not cause skin irritation/corrosion in the animals tested. Thus the substance is not classified as a skin irritant/corrosive.
Eye irritation
A GLP compliant study (OECD 405) was conducted to determine the eye irritation/corrosion potential of the substance.
The substance caused reversible eye redness in 1/3 animals at the 24 hours time point. However, as the mean score (24, 48 and 72 hours) for the redness was lower than 2 thus classification according to Regulation (EC) No 1272/2008 is not required. The substance did not cause corrosion or classifiable irritation in the eye. Respiratory irritationThere is no data for respiratory irritation, the weight of evidence would suggest that respiratory irritation is unlikely to occur.
Justification for classification or non-classification
The substance did not cause skin irritation/corrosion in any other the animals tested, thus classification according to Regulation (EC) No 1272/2008 is not required.
The substance caused reversible eye redness in 1/3 animals at the 24 hours time point. However, as the mean score (24, 48 and 72 hours) for the reddness was lower than 2 thus classification according to Regulation (EC) No 1272/2008 is not required.
There is no data for respiratory irritation, the weight of evidence coupled with the physiochemical properties would suggest that respiratory irritation is unlikely to occur. Thus classification according to Regulation (EC) No 1272/2008 is not required.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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