Registration Dossier
Registration Dossier
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EC number: 402-070-1 | CAS number: 88122-99-0 UVINUL T 150
Endpoint summary
Administrative data
Description of key information
Biodegradation in water
The ready biodegradation oftest chemicalwas conducted in accordance to OECD guideline 301C (Ready Biodegradability: Modified MITI Test (I)) and 79/831/EWG Annex V, Part C.5.2, respectively for 28 days. Aniline was used as a reference substance for the study. Reference substance undergoes 80% degradation in 28 days. No degradation oftest chemicalwas observed using BOD parameter after a period of 28 days. Therefore, it is concluded that the test chemical was not readily biodegradable in water.
Biodegradation in water and sediment
Estimation Programs Interface (2018) prediction model was run to predict the half-life in water and sediment for the test chemical. If released in to the environment, 13.4% of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of test chemical in water is estimated to be 60 days (1440 hrs). The half-life (60 days estimated by EPI suite) indicates that the chemical is persistent in water and the exposure risk to aquatic animals is moderate to high whereas the half-life period of test chemical in sediment is estimated to be 541.66 days (13000 hrs). However, as the percentage release of test chemical into the sediment is less than 1% (i.e, reported as 0.00192%), indicates that test chemical is not persistent in sediment.
Biodegradation in soil
The half-life period of test chemical in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (2018). If released into the environment, 86.5% of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of test chemical in soil is estimated to be 120 days (2880 hrs). Based on this half-life value of test chemical, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is moderate to low.
Additional information
Biodegradation in water
Various experimental studies of the test chemical were reviewed for determining the biodegradability of test chemical and their results are summarized below:
In an experimental key study,the ready biodegradation oftest chemicalwas conducted in accordance to OECD guideline 301C (Ready Biodegradability: Modified MITI Test (I)) and 79/831/EWG Annex V, Part C.5.2, respectively for 28 days. Aniline was used as a reference substance for the study. Reference substance undergoes 80% degradation in 28 days. No degradation oftest chemicalwas observed using BOD parameter after a period of 28 days. Therefore, it is concluded that the test chemical was not readily biodegradable in water.
Another biodegradation study was conducted according to the manometric respirometry test for determining the biodegradability of the test chemical for 28 days. Aniline was used as a reference substance for the study. The percentage degradation of test chemical was determined to be 0% after a period of 28 days. Thus, based on percentage degradation, test chemical is considered to be not readily biodegradable in nature.
On the basis of above results, it is concluded that test chemical is expected to be not readily degradable in nature.
Biodegradation in water and sediment
Estimation Programs Interface (2018) prediction model was run to predict the half-life in water and sediment for the test chemical. If released in to the environment, 13.4% of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of test chemical in water is estimated to be 60 days (1440 hrs). The half-life (60 days estimated by EPI suite) indicates that the chemical is persistent in water and the exposure risk to aquatic animals is moderate to high whereas the half-life period of test chemical in sediment is estimated to be 541.66 days (13000 hrs). However, as the percentage release of test chemical into the sediment is less than 1% (i.e, reported as 0.00192%), indicates that test chemical is not persistent in sediment.
Biodegradation in soil
The half-life period of test chemical in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (2018). If released into the environment, 86.5% of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of test chemical in soil is estimated to be 120 days (2880 hrs). Based on this half-life value of test chemical, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is moderate to low.
On the basis of available information, the test chemical can be considered to be not readily biodegradable in nature.
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