Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 294-600-1 | CAS number: 91744-38-6
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
The sensitizing potential of the test substance (CAS 91744-38-6, Glycerides, C16-18 mono-, di- and tri-, hydrogenated, citrates, potassium salts) was investigated in a study according to OECD Guideline No. 406.
Under the conditions of the test no sensitizing effects of the test substance could be observed. In addition, no clinical effects were observed. Body weight increase of the test animals was comparable to the control.
This result is supported by a second study in which the sensitizing potential of the analogue substance CAS 91744-23-9 was also investigated in an OECD 406 study. The substance concentrations were 2, 25, 50 and 100 % in corn oil. Animal sites were graded according to the Magnusson and Kligman grading scale for the evaluation of challenge patch test reactions. No animals of the test or control groups produced reactions at either the test or vehicle control sites, at the 24 or 48 h readings.
Migrated from Short description of key information:
OECD 406 studies are available for the test substance (Collier, 1981) and a structural analogue (Krueger, 1996). In both studies no animals of the test or control groups produced reactions at either the test or vehicle control sites, at the 24 or 48 h readings.
Justification for selection of skin sensitisation endpoint:
Key study for sensitisation endpoint. Study was conducted according to OECD 406 under GLP.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
No sensitizing effect was observed at appropriate dose levels.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
