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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Classification & Labelling & PBT assessment

PBT assessment

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Administrative data

PBT assessment: overall result

Reference
Name:
[(2S, 3R, 5S)-3-acetoxy-5-(5-methyl-2,4-diSUBSTITUTED-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl acetate
Type of composition:
boundary composition of the substance
State / form:
solid: particulate/powder
Reference substance:
[(2S, 3R, 5S)-3-acetoxy-5-(5-methyl-2,4-diSUBSTITUTED-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl acetate
PBT status:
the substance is not PBT / vPvB
Justification:

The substance has low logKow value (logKow 1) and is not of greater concern because it has low potential to bio-concentrate in living organisms.

The substance is sensitizing, non-mutagenic in vitro, non- irritating, and non-toxic orally in an acute study.