Registration Dossier
Registration Dossier
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EC number: 208-591-9 | CAS number: 534-17-8
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- no data
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
Data source
Referenceopen allclose all
- Reference Type:
- secondary source
- Title:
- Clastogenic effects of cesium chloride on mouse bone marrow cells in vivo
- Author:
- Ghosh, A.; Sharma, A.; Talukder, G.
- Year:
- 1 990
- Bibliographic source:
- Mutation Research, 244, 295-298
- Reference Type:
- review article or handbook
- Title:
- Toxicity Profile Cesium compounds (2000)
- Author:
- bibra toxicology advice & consulting
- Year:
- 2 000
- Bibliographic source:
- PW/jab/November 1999(f)/P.489/T.2090/ACN123222
- Reference Type:
- secondary source
- Title:
- Cytogenetic damage induced in vivo to mice by single exposure to cesium chloride
- Author:
- Ghosh, A.; Sharma, A; Talukder, G.
- Year:
- 1 991
- Bibliographic source:
- Environmental and Molecular Mutagenesis, 18, 87-91
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: no data
- GLP compliance:
- not specified
- Test type:
- other: no data
Test material
- Reference substance name:
- Caesium chloride
- EC Number:
- 231-600-2
- EC Name:
- Caesium chloride
- Cas Number:
- 7647-17-8
- Molecular formula:
- ClCs
- IUPAC Name:
- cesium;chloride
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- other: Swiss albino mice (Mus musculus)
- Sex:
- female
Administration / exposure
- Route of administration:
- other: oral
Results and discussion
Effect levelsopen allclose all
- Sex:
- female
- Dose descriptor:
- LD50
- Effect level:
- 2 500 mg/kg bw
- Based on:
- test mat.
- Key result
- Sex:
- female
- Dose descriptor:
- LD50
- Effect level:
- 2 420 mg/kg bw
- Based on:
- other: calculated as cesium carbonate
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- The oral LD50 value of cesium chloride in mice was determined to be 2600 mg/kg bw. Calculated as cesium carbonate the LD50 value is 2420 mg/kg bw.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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