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EC number: 257-182-1 | CAS number: 51410-72-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 1.012 mg/L
- Assessment factor:
- 50
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 1 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.101 mg/L
- Assessment factor:
- 500
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 9 000 mg/L
- Assessment factor:
- 1
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 3.67 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.367 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.14 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
PNEC aqua (freshwater)
Freshwater aquatic toxicity studies with MAPTAC were conducted in fish, invertebrates, and algal species. Acute toxicity studies were conducted in fish and algae. Chronic studies are available for algae and invertebrates. Aquatic invertebrates were the most sensitive trophic level in chronic studies.
The PNEC aqua (freshwater) was based on the EC10 of 50.6 mg/L determined in a 21 d reproduction study with Daphnia magna. Two chronic studies were available for this substance, which covered two trophic levels (algal and invertebrates). Since similar short-term toxicity was observed between trophic levels with all L(E)C50 values in a similar range, an assessment factor of 50 was applied to the EC10 to calculate the PNEC aqua (freshwater) in accordance with Guidance on information requirements and chemical safety assessment, Chapter R.10: Characterisation of dose [concentration]-response for environment, 2008.
PNEC aqua (marine)
No tests with marine species are available. The PNEC aqua (marine) was based on the EC10 of 50.6 mg/L determined in a 21 d reproductions study with Daphnia magna. An assessment factor of 500 was applied to the EC10 to calculate the PNEC aqua (marine) in accordance with Guidance on information requirements and chemical safety assessment, Chapter R.10: Characterisation of dose [concentration]-response for environment, 2008.
PNEC aqua (intermittent release)
The PNEC aqua (intermittent release) was based on the lowest acute toxicity value of 100 mg/L for Desmodesmus subspicatus (72 h EC50). Based on the available data set, an assessment factor of 100 was applied to the lowest EC50 to calculate the PNEC aqua (intermittent release) in accordance with Guidance on information requirements and chemical safety assessment, Chapter R.10: Characterisation of dose [concentration]-response for environment, 2008..
PNEC STP
The PNEC STP was based on the 16 h EC10 of 9000 mg/L in a Bringman-Kühn test in Pseudomonas putida. Based on the available data, an assessment factor of 1 was applied to calculate the PNEC STP in accordance with Guidance on information requirements and chemical safety assessment, Chapter R.10: Characterisation of dose [concentration]-response for environment, 2008..
PNEC sediment (freshwater, marine)
No toxicity data for sediment dwelling organisms are available. Thus, the PNEC for freshwater as well as marine sediment has been calculated with the equilibrium partitioning method using EUSES 2.1.
The following data have been taken into account for the calculation:
Molecular weight [g/mol] |
220.74 |
Melting point [°C] |
54.00 |
Boiling point [°C] |
|
Vapour pressure [Pa], 25°C |
0.001 |
Water solubility [mg/L], 20°C |
1000000000 |
Log Kow |
-2.58 |
Koc (Kow method) |
0.2428 |
PNEC aqua, freshwater[mg/L] |
1.012 |
PNEC aqua, marine [mg/L] |
0.1012 |
PNEC soil
No toxicity data for soil organisms are available. Thus, the PNEC for freshwater as well as marine sediment has been calculated with the equilibrium partitioning method using EUSES 2.1.
The following data have been taken into account for the calculation:
Molecular weight [g/mol] |
220.74 |
Melting point [°C] |
54.00 |
Boiling point [°C] |
|
Vapour pressure [Pa], 25°C |
0.001 |
Water solubility [mg/L], 20°C |
1000000000 |
Log Kow |
-2.58 |
Koc (Kow method) |
0.2428 |
PNEC aqua, freshwater[mg/L] |
1.012 |
PNEC oral
A PNEC oral was not calculated for MAPTAC due to the calculated log Kow of -2.58 indicating that there would be only little or no biomagnification of the test substance in the food chain.
Conclusion on classification
Based on the available reliable and relevant data, short-term toxicity values (L(E)C50) for fish and algae are >1 mg/L. MAPTACdoes not need to be classified for acute toxicity to aquatic organisms according to Directive 67/548/EEC or Regulation EC No 1272/2008.
Based on the available reliable and relevant data, long-term toxicity values (EC10) for aquatic invertebrates and algae are > 1 mg/L, and MAPTAC is not readily biodegradable (inherently biodegradble). Thus, MAPTACdoes not need to be classified for chronic toxicity to aquatic organisms according to Regulation EC No 1272/2008.
No classification for chronic toxicity to aquatic organisms according to Directive 67/548/EEC is required based on the available short-term toxicity values (> 100 mg/L) and inherent biodegradability.
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