Registration Dossier
Registration Dossier
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EC number: 257-182-1 | CAS number: 51410-72-1
Toxicity to microorganisms
Administrative data
- Endpoint:
- toxicity to microorganisms
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1987-11-25
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Basic data given: comparable to standards. No GLP. Very limited documentation.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 988
- Report date:
- 1988
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Guideline:
- other: Bringmann-Kühn test similar to later implemented DIN 38412 part 8
- Principles of method if other than guideline:
- Bringmann-Kühn test
- GLP compliance:
- no
Test material
- Reference substance name:
- (3-methacrylamidopropyl)trimethylammonium chloride
- EC Number:
- 257-182-1
- EC Name:
- (3-methacrylamidopropyl)trimethylammonium chloride
- Cas Number:
- 51410-72-1
- Molecular formula:
- C10 H21 N2 O. Cl
- IUPAC Name:
- trimethyl-[3-(2-methylprop-2-enoylamino)propyl]azanium chloride
- Test material form:
- other: liquid
- Details on test material:
- - Name of test material (as cited in study report): MAPTAC
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
- Details on sampling:
- no data
Test solutions
- Vehicle:
- no
- Details on test solutions:
- no data
Test organisms
- Test organisms (species):
- Pseudomonas putida
- Details on inoculum:
- no data
Study design
- Test type:
- not specified
- Water media type:
- not specified
- Limit test:
- yes
- Total exposure duration:
- 16 h
- Remarks on exposure duration:
- not given in test report, but standard exposure time in the Bringmann-Kühn test is 16 h
- Post exposure observation period:
- no
Test conditions
- Hardness:
- no data
- Test temperature:
- no data
- pH:
- no data
- Dissolved oxygen:
- no data
- Salinity:
- no data
- Nominal and measured concentrations:
- not given in the report
- Details on test conditions:
- TEST CONCENTRATIONS
not given in the report - Reference substance (positive control):
- not specified
Results and discussion
Effect concentrations
- Duration:
- 16 h
- Dose descriptor:
- EC10
- Effect conc.:
- 18 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth inhibition
- Details on results:
- - sample insoluble in water
- Results with reference substance (positive control):
- no data
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- In this study (Bringmann-Kühn test), the EC10 of MAPTAC in Pseudomonas putida was 18000 mg/L (9000 mg a.i./L).
- Executive summary:
In a 16-h toxicity study conducted according to the Bringmann-Kühn test, cultures of Pseudomonas putida were exposed to MAPTAC (tested concentrations not given in the report).
The EC10 was 18000 mg/L (corresponding to 9000 mg a.i./L).
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