Registration Dossier
Registration Dossier
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EC number: 223-453-8 | CAS number: 3900-45-6
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- migrated information: read-across based on grouping of substances (category approach)
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Chapman & Hall Number: FPT10-V
- Author:
- Chapman & Hall
- Year:
- 2 012
- Bibliographic source:
- Combined Chemical Dictionary, Version 6.1
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- Data is from handbook of 'CCD (Combined Chemical Dictionary)'
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2'-acetonaphthone
- EC Number:
- 202-216-2
- EC Name:
- 2'-acetonaphthone
- Cas Number:
- 93-08-3
- Molecular formula:
- C12H10O
- IUPAC Name:
- 1-(2-naphthyl)ethanone
- Test material form:
- solid: crystalline
- Details on test material:
- - Name of test material (as cited in study report): 2'-acetonaphthone
- Substance type: Organic
- Physical state: Solid
Constituent 1
Test animals
- Species:
- human
Test system
- Type of coverage:
- not specified
- Preparation of test site:
- not specified
- Vehicle:
- not specified
- Controls:
- not specified
Results and discussion
In vivo
Results
- Irritation parameter:
- overall irritation score
- Basis:
- mean
- Remarks on result:
- other: Skin irritant
Applicant's summary and conclusion
- Interpretation of results:
- irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The substance 2'-acetonaphthone gives positive result for skin irritation when applied on human skin.
- Executive summary:
The substance 2'-acetonaphthone gives positive result for skin irritation when applied on human skin.
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