Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
dermal absorption
Type of information:
(Q)SAR
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
other: QSAR Database
Title:
Unnamed
Year:
2012
Report date:
2012

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: REACH guidance on QSARs R.6, May/July 2008

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
435-740-7
EC Name:
-
Cas Number:
94317-64-3
Molecular formula:
C4H14N3PS
IUPAC Name:
Phosphorothioic triamide, N-butyl-
Constituent 2
Reference substance name:
N-(n-butyl) thiophosphoric triamide (NBPT)
IUPAC Name:
N-(n-butyl) thiophosphoric triamide (NBPT)

Results and discussion

Absorption in different matrices:
Dermal absorption of the test substance was predicted to be medium high with an estimated dermal permeability coefficient (Kp) 0.000181 cm/hr.

Applicant's summary and conclusion