Registration Dossier
Registration Dossier
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EC number: 248-704-9 | CAS number: 27871-49-4
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- adult fish: sub(lethal) effects
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
Reference
Description of key information
The chemical safety assessment of methyl (S)-lactate did not indicate the need for long-term testing on fish. Thus, this endpoint is waived.
Key value for chemical safety assessment
Additional information
Column 2 of Annex IX of Regulation (EC) No 1907/2006 specifies that long-term toxicity testing shall be proposed by the registrant if the chemical safety assessment according to Annex I indicates the need to investigate further the effects on fish. Since short-term effect concentrations of methyl-(S)-lactate on fish were above 100 mg/L, i.e. the guideline-compliant limit concentration, which is the concentration relevant for classification and labelling, long-term toxicity tests on fish need not be conducted. Furthermore, methyl (S)-lactate is readily biodegradable (see section 5.2.1) and as a consequence, no chronic exposure of fish is expected. Therefore, and for reasons of animal welfare, a long-term toxicity study in fish is not provided.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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