Registration Dossier
Registration Dossier
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EC number: 268-899-4 | CAS number: 68153-95-7 This substance is identified by SDA Substance Name: C12-C18 dialkyl amine and SDA Reporting Number: 16-042-00.
Toxicity to microorganisms
Administrative data
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1991
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 991
- Report date:
- 1991
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
- GLP compliance:
- yes
Test material
- Reference substance name:
- Amines, di-C12-18-alkyl
- EC Number:
- 268-899-4
- EC Name:
- Amines, di-C12-18-alkyl
- Cas Number:
- 68153-95-7
- Molecular formula:
- R2-NH whereas R = mainly C12-18 (even numbered) alkyl molecular weight range is based on R =12 (lower limit value) and R = 18 (higher limit value)
- IUPAC Name:
- N-C12-18-(even numbered)-alkyl-1-C12-18-(even numbered)-amine
- Details on test material:
- - Analytical purity: 100%
- Purity test date: 02-05-1991
- Expiration date of the lot/batch: 02-05-1993
- Stability under test conditions: stable
Constituent 1
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
PHYSICO-CHEMICAL PROPERTIES
- Water solubility (under test conditions): not soluble
- pH dependance on stability: alkalic
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- activated sludge of a predominantly domestic sewage
- Details on inoculum:
- - Laboratory culture:
- Method of cultivation: aerobic, waterlike medium
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 3 h
Test conditions
- Test temperature:
- 18-22 C
- Nominal and measured concentrations:
- nominal: 100, 180, 320, 580, 1000 mg/L:
- Reference substance (positive control):
- yes
- Remarks:
- Copper (II) sulphatepentahydrate
Results and discussion
Effect concentrations
- Duration:
- 3 h
- Dose descriptor:
- EC50
- Effect conc.:
- 350 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
- Remarks on result:
- other: 166-736 mg/L
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
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