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Environmental fate & pathways

Biodegradation in water: screening tests

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Administrative data

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Description of key information

Readily biodegradable: 93.1% (CO2 evolution) in 28 days (OECD 301 B); read-across

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information

Since no studies investigating the ready biodegradability of Decanoic acid, mixed esters with neopentyl glycol and octanoic acid (CAS No. 70693-32-2) are available, in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5, a read across to the structurally related category members 2,2-dimethyl-1,3-propanediyl dioctanoate (CAS No. 31335-74-7) and Fatty acids, C8-18 and C18-unsatd., esters with neopentyl glycol (CAS No. 85186-86-3) was conducted. All three substances are esters of neopentyl glycol with different fatty acids. Decanoic acid, mixed esters with neopentyl glycol and octanoic acid (CAS No. 70693-32-2) is a UVCB consisting of C8 and C10 fatty acids. C8 is covered by the read-across to 2,2-dimethyl-1,3-propanediyl dioctanoate (CAS No. 31335-74-7), which is a NPG ester with C8 fatty acids. Fatty acids, C8-18 and C18-unsatd., esters with neopentyl glycol (CAS No. 85186-86-3) is a UVCB consisting of NPG esters of C12 to C18 fatty acids. Since both read-across substances are readily biodegradable, Decanoic acid, mixed esters with neopentyl glycol and octanoic acid (CAS No. 70693-32-2) is expected to be readily biodegradable as well. Furthermore, as can be seen in the data matrix of the category justification in Section 13, all reliable data in the category support the biodegradability assessment, by showing a consistent pattern of results.

The key ready biodegradability study carried out with Fatty acids, C8-18 and C18-unsatd., esters with neopentyl glycol (CAS No. 85186-86-3), was performed following the OECD Guideline 301 B (Häner, 2006). Activated sludge was used as inoculum. During the 28-day test period, biodegradation reached 90.2%, based on CO2 evolution, and the 10-day window criterion was met.

The key ready biodegradability study carried out with 2,2-dimethyl-1,3-propanediyl dioctanoate (CAS No. 31335-74-7), was performed following the OECD Guideline 301 B (Bouillon, 1999). Activated sludge was used as inoculum. During the 28-day test period, biodegradation reached 93.1%, based on CO2 evolution, and the 10-day window criterion was met.

In conclusion, Decanoic acid, mixed esters with neopentyl glycol and octanoic acid (CAS No. 70693-32-2) can be considered readily biodegradable according to OECD criteria.

Thus, based on theabove mentioned results, and due to the structural and profile similarities of the substances, as are explained in the overall endpoint summary (IUCLID Chapter 5), Decanoic acid, mixed esters with neopentyl glycol and octanoic acid (CAS No. 70693-32-2) can be considered readily biodegradable.