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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2007
Report date:
2007

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.2 (Boiling Temperature)
Deviations:
no
GLP compliance:
yes
Type of method:
differential thermal analysis

Test material

Constituent 1
Reference substance name:
1H-Isoindole-1,3(2H)-dione, 2-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-
IUPAC Name:
1H-Isoindole-1,3(2H)-dione, 2-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-
Constituent 2
Chemical structure
Reference substance name:
2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione
EC Number:
610-200-5
Cas Number:
446292-07-5
Molecular formula:
C21 H21 N3 O5
IUPAC Name:
2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione

Results and discussion

Boiling point
Decomposition:
yes
Decomp. temp.:
290 °C
Remarks on result:
other: There is no boiling point up to the decomposition of the test item, pressure not reported

Applicant's summary and conclusion

Conclusions:
The sample is closed up in a crucible made of aluminium with perforated Iid and heated up in a DTA-system (heating rate 5 K/min). In comparison with an inert sample the temperature difference and the heat effect is recorded. The boiling curve of the sample is a steep endothermic signal. There is no boiling point up to the decomposition of the test item. The exothermal decomposition starts at 290°C.
Executive summary:

There is no boiling point up to the decomposition of the test item. The exothermal decomposition starts at 290°C (Bayer Study, 2007).