Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 209-127-8 | CAS number: 556-50-3
Particle size distribution (Granulometry)
Administrative data
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 17-22 July 2020
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 020
- Report date:
- 2020
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7520 (Particle Size, Fiber Length, and Diameter Distribution)
- Version / remarks:
- 1996
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- ISO 13320 (Particle size analysis - Laser diffraction methods)
- Version / remarks:
- 2009
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)
- Version / remarks:
- 1981
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- Laser scattering/diffraction
Test material
- Reference substance name:
- N-glycylglycine
- EC Number:
- 209-127-8
- EC Name:
- N-glycylglycine
- Cas Number:
- 556-50-3
- Molecular formula:
- C4H8N2O3
- IUPAC Name:
- N-glycylglycine
- Test material form:
- solid: crystalline
- Details on test material:
- Batch Number: S119 0711
Storage conditions: room temperature
Constituent 1
- Specific details on test material used for the study:
- Batch No.: S119 0711
Storage: At room temperature (approx. 15-25°C), dry
Results and discussion
Particle sizeopen allclose all
- Key result
- Percentile:
- D90
- Mean:
- 222.1 µm
- St. dev.:
- 1.15
- Remarks on result:
- other: Average result calculated from the results of two test series
- Key result
- Percentile:
- D50
- Mean:
- 62.3 µm
- St. dev.:
- 0.33
- Remarks on result:
- other: Average result calculated from the results of two test series
- Key result
- Percentile:
- D10
- Mean:
- 9.5 µm
- St. dev.:
- 0.09
- Remarks on result:
- other: Average result calculated from the results of two test series
Any other information on results incl. tables
Light microscopy
The optically investigation of the test item with different magnifications has been investigated. For a better visualization a 10x10 grid with 100 µm squares was used.
At 5x and 20x magnifications bigger particles can be observed. Examining the 50x magnification, the test item consists of crystalline particles.
Particle size distribution
Two test series of 3 measurements each were performed with the fine fraction of the test item.
Test series 1:
| Percentile | Particle size (µm) | Standard deviation |
| D10 | 9.6 | 0.35 |
| D50 | 62.6 | 1.48 |
| D90 | 223.3 | 6.45 |
Test series 2:
| Percentile | Particle size (µm) | Standard deviation |
| D10 | 9.4 | 0.15 |
| D50 | 61.9 | 0.53 |
| D90 | 221.0 | 1.98 |
Applicant's summary and conclusion
- Conclusions:
- The test item Glycyl glycine (CAS no. 556-50-3) has median particle size of D50 = 62.3 µm, which was determined by laser diffraction measurement according to OECD Test Guideline 110 (1981), ISO 13320 (2009) and EPA OCSPP Guideline OPPTS 830.7520 (1996).
- Executive summary:
The test item Glycyl-glycine (CAS no. 556-50-3) has median particle size of D50 = 62.3 µm, which was determined by laser diffraction measurement according to OECD Test Guideline 110 (1981), ISO 13320 (2009) and EPA OCSPP Guideline OPPTS 830.7520 (1996).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
