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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
thermal stability
Type of information:
experimental study
Adequacy of study:
key study
Study period:
25 June - 23 October 2020
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2020
Report date:
2020

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
other: UN Manual of Tests and Criteria
Version / remarks:
7th edition
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 113 (Screening Test for Thermal Stability and Stability in Air)
Version / remarks:
1981
Deviations:
no
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
N-glycylglycine
EC Number:
209-127-8
EC Name:
N-glycylglycine
Cas Number:
556-50-3
Molecular formula:
C4H8N2O3
IUPAC Name:
N-glycylglycine
Test material form:
solid: crystalline
Details on test material:
Batch Number: S119 0711
Storage conditions: room temperature

Results and discussion

For thermal stability study

Test substance thermally stable:
yes
Operating temperature
Key result
Operating temp.:
ca. 20 - <= 500 °C
Remarks on result:
other: an endothermic effect starting at a temperature of approx. 210°C was observed (melting of the test item). A second endothermic effect was observed starting at a temperature of approx. 250°C (decomposition of test item starting at approx. 230°C)

Any other information on results incl. tables

The test item in closed glass crucibles showed an endothermic effect starting at a temperature of approx. 210 °C, which can be assigned to the melting of the test item accompanied its decomposition. A second endothermic effect was observed starting at a temperature of approx. 250 °C. The results of the DSC-measurements are summarized below:
























Measurement No.



Sample weight / mg



Onset / °C



Energy / J/g



PN19900



5.02



210
250



+300 (endothermic)
+170 (endothermic)



PN19906



4.02



210
250



+290 (endothermic)
+150 (endothermic)


Applicant's summary and conclusion

Conclusions:
The test item Glycyl glycine (CAS no. 556-50-3) showed an endothermic effect starting at a temperature of approx. 210 °C, which can be assigned to the melting of the test item accompanied by its decomposition. A second endothermic effect was observed starting at a temperature of approx. 250 °C.
Executive summary:

The test item Glycyl glycine (CAS no. 556-50-3) showed an endothermic effect starting at a temperature of approx. 210 °C, which can be assigned to the melting of the test item accompanied by its decomposition. A second endothermic effect was observed starting at a temperature of approx. 250 °C.