Registration Dossier
Registration Dossier
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EC number: 947-879-5 | CAS number: 2475232-73-4
pH
Administrative data
- Endpoint:
- pH
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 122 (Determination of pH, Acidity and Alkalinity)
- Version / remarks:
- 26 July 2013
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 4-[3-(3,5-dichloro-4-fluorophenyl)-4,4,4-trifluorobut-2-enoyl]-N-(2-ethyl-3-oxo-1,2-oxazolidin-4-yl)-2-methylbenzamide
- Molecular formula:
- C23H18Cl2F4N2O4
- IUPAC Name:
- 4-[3-(3,5-dichloro-4-fluorophenyl)-4,4,4-trifluorobut-2-enoyl]-N-(2-ethyl-3-oxo-1,2-oxazolidin-4-yl)-2-methylbenzamide
- Test material form:
- solid
- Details on test material:
- Off-white
Constituent 1
Reagents
- Reagent:
- water
Results and discussion
pH value
- Key result
- pH value:
- 5.69
- Temp.:
- 20 °C
- Concentration:
- 1 other: % w/v
Applicant's summary and conclusion
- Conclusions:
- The pH value of the test substance, as a 1% w/v aqueous dispersion, was 5.69 at 20 °C.
- Executive summary:
The pH value of the test substance, as a 1% w/v aqueous dispersion, was determined under GLP to OECD TG 122. An aliquot of test substance of about 1 g was added to 50 mL of high purity water (with a specification of resistance >18.2 MΩ and TOC <5 ppb, equilibrated to 20 °C), and the sample was then made up to 100 mL with the same high purity water before being shaken vigorously for one minute. The sample was then transferred to a sample cup and allowed to settle for a period of one minute. The pH value was then recorded from the pH meter, without stirring of the sample, after this equilibration. A second reading was recorded after a period of 2 minutes. Two determinations of the pH value were done in this way, and the overall mean was 5.69 at 20 °C.
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