Registration Dossier
Registration Dossier
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EC number: 249-793-7 | CAS number: 29710-25-6
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
- Justification for type of information:
- JUSTIFICATION FOR DATA WAIVING
Column 2 of Annex VII of REACH Regulation states an adaptation from column 1: if there are any mitigating factors indicating that the aquatic toxicity is unlikely to occur, the study has not to be performed.
According to the ECHA guidance (Chapter R.7b: Endpoint specific guidance, 2017) a study does not need to be conducted if there are mitigating factors indicating that aquatic toxicity is unlikely to occur (e.g. the substance is highly insoluble in water or the substance is unlikely to cross biological membranes).
According to the available data (Company experimental internal data, estimated data and data collected from scientific literature) the water solubility of the substance ranges from
(i) <1 mg/L (determined by Flask Method (according to Regulation N. 440/2008), it means that it has a value of detection below the limit of quantification of the method.
(ii) 2.132e-005 mg/L (estimated by EPI SuiteTM v4.11, model used: WSKOW v1.42).
Moreover, in the relevant scientific literature the substance is recognized as insoluble in water.
Data source
Materials and methods
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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