Registration Dossier
Registration Dossier
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EC number: 206-337-1 | CAS number: 328-84-7
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation: in vivo (non-LLNA)
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
Data source
Referenceopen allclose all
- Reference Type:
- study report
- Title:
- Unnamed
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 978
Materials and methods
- Principles of method if other than guideline:
- Buehler Test
- GLP compliance:
- no
Test material
- Test material form:
- liquid
- Details on test material:
- Clear colourless liquid
- Specific details on test material used for the study:
- Purity: not reported
In vivo test system
Test animals
- Species:
- guinea pig
- Details on test animals and environmental conditions:
- Weight: 200 - 300 g
Study design: in vivo (non-LLNA)
Induction
- Route:
- epicutaneous, occlusive
- Vehicle:
- other: ethanol
- Concentration / amount:
- 10% [w/v]
- Day(s)/duration:
- 21
- Details on study design:
- Two Challenge applications 14 days after induction were applied to determine local and systemic effects.
Results and discussion
Applicant's summary and conclusion
- Conclusions:
- Under the conditions of this test 3,4-Dichlorobenzotrifluoride was not sensitizing in guinea pigs.
- Executive summary:
No sensitization was observed.
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