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Diss Factsheets

Physical & Chemical properties

Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
07 February 2003 - 29 May 2003
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: The study was conducted according to OECD and EC test guidelines, and in compliance with GLP.
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
isoteniscope
Specific details on test material used for the study:
- Analytical purity: 99.9%
- Lot/batch No.: 020618
Key result
Temp.:
25 °C
Vapour pressure:
4 270 Pa
Remarks on result:
other: Mean value is 4270 Pa ± 2.8%

Four replicate runs of vapour pressure measured at a series of temperatures between 15°C to 50°C were conducted. The first run did not give a linear relationship between log10 Vp and 1/T and therefore could be used to calculate an accurate value for the vapour pressure of the substance. Runs 2, 3, and 4 did give a linear relationship between log10Vp and 1/T; the quoted result is based on the mean value calculated from runs 2, 3, and 4.

Conclusions:
The mean vapour pressure of the test substance at 25°C is 4270 Pa ±2.8%.

Description of key information

Vapour pressure of the test substance at 25°C = 4270 Pa

Key value for chemical safety assessment

Vapour pressure:
4 270 Pa
at the temperature of:
25 °C

Additional information

A measurement of vapour pressure was conducted as part of a package of physicochemical testing on the substance (Huntingdon Life Sciences, 2003, Study ZCE111). The study was conducted in compliance with GLP and the vapour pressure measurement was performed according to EC and OECD test guidelines. The vapour pressure measurement was performed by the isoteniscope method.

The vapour pressure of the test substance was found to be 4270 Pa at 25°C.