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EC number: 249-670-8 | CAS number: 29508-47-2
Endpoint summary
Administrative data
Description of key information
Biodegradation in water: screening tests
Estimation Programs Interface Suite (EPI suite, 2017) was run to predict the biodegradation potential of the5-[[p-(benzylmethylamino)phenyl]azo]-1,4-dimethyl-1H-1,2,4-triazolium chloride (CAS: 29508-47-2)in the presence of mixed populations of environmental microorganisms. The biodegradability of the substance was calculated using seven different models such as Linear Model, Non-Linear Model, Ultimate Biodegradation Timeframe, Primary Biodegradation Timeframe, MITI Linear Model, MITI Non-Linear Model and Anaerobic Model (called as Biowin 1-7, respectively) of the BIOWIN v4.10 software. The results indicate that5-[[p-(benzylmethylamino)phenyl]azo]-1,4-dimethyl-1H-1,2,4-triazolium chloride (CAS: 29508-47-2) is expected to be not readily biodegradable.
Biodegradation in water and sediment
Estimation Programs Interface (EPI Suite, 2017) prediction model was run to predict the half-life in water and sediment for the test compound5-[[p-(benzylmethylamino)phenyl]azo]-1,4-dimethyl-1H-1,2,4-triazolium chloride(CAS No: 29508 -47 -2). If released in to the environment,7.61% of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of5-[[p-(benzylmethylamino)phenyl]azo]-1,4-dimethyl-1H-1,2,4-triazolium chloride
in water is estimated to be 60 days (1440hrs). The half-life (60 days estimated by EPI suite) indicates that the chemical is persistent in water, whereas the half-life period of5-[[p-(benzylmethylamino)phenyl]azo]-1,4-dimethyl-1H-1,2,4-triazolium chloridein sediment is estimated to be 123.33 days (2960hrs). Based on this half-life value, it indicates that5-[[p-(benzylmethylamino)phenyl]azo]-1,4-dimethyl-1H-1,2,4-triazolium chlorideis persistent in sediment.
Biodegradation in soil
The half-life period of5-[[p-(benzylmethylamino)phenyl]azo]-1,4-dimethyl-1H-1,2,4-triazolium chloride (CAS: 29508-47-2)in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (EPI suite, 2017). If released into the environment,84.3% of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of5-[[p-(benzylmethylamino)phenyl]azo]-1,4-dimethyl-1H-1,2,4-triazolium chloride (CAS: 29508-47-2)in soil is estimated to be120 days (2880hrs). Based on this half-life value of5-[[p-(benzylmethylamino)phenyl]azo]-1,4-dimethyl-1H-1,2,4-triazolium chloride (CAS: 29508-47-2), it is concluded that the chemical is persistent in the soil environment.
Additional information
Biodegradation in water: screening tests
Following studies include the predicted data and experimental study for the target chemical and structurally similar read acoss to conclude the extent of
5-[[p-(benzylmethylamino)phenyl]azo]-1,4-dimethyl-1H-1,2,4-triazolium chloride (CAS: 29508-47-2)towards Biodegradability in water is summarized as follows:
Estimation Programs Interface Suite (EPI suite, 2017) was run to predict the biodegradation potential of the5-[[p-(benzylmethylamino)phenyl]azo]-1,4-dimethyl-1H-1,2,4-triazolium chloride (CAS: 29508-47-2)in the presence of mixed populations of environmental microorganisms. The biodegradability of the substance was calculated using seven different models such as Linear Model, Non-Linear Model, Ultimate Biodegradation Timeframe, Primary Biodegradation Timeframe, MITI Linear Model, MITI Non-Linear Model and Anaerobic Model (called as Biowin 1-7, respectively) of the BIOWIN v4.10 software. The results indicate that5-[[p-(benzylmethylamino)phenyl]azo]-1,4-dimethyl-1H-1,2,4-triazolium chloride (CAS: 29508-47-2) is expected to be not readily biodegradable.
Similar predicted data for the target chemical suggests that the Biodegradability of 5-[[p-(benzylmethylamino)phenyl]azo]-1,4-dimethyl-1H-1,2,4-triazolium chloride (CAS: 29508-47-2) is predicted using OECD QSAR toolbox version 3.3 with log Kow as the primary descriptor. Test substance undergoes 0.91 % degradation by BOD in 28 days. Thus, based on percentage degradation, the test chemical 5-[[p-(benzylmethylamino)phenyl]azo]-1,4-dimethyl-1H-1,2,4-triazolium chloride (CAS: 29508-47-2) was estimated to be not readily biodegradable in water.
The above predicted data of target chemical is supported by the experimental study of structurally similar read across C.I. Solvent Red 49 (CAS no. 509 -34 -2) from the authoritative database J-CHECK 2017, suggests that theBiodegradation study was conducted for 28 days for evaluating the percentage biodegradability of test substance C.I. Solvent Red 49 (CAS no. 509 -34 -2). Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l. The percentage degradation of test substance was determined to be 0 and 1% degradation by BOD, TOC removal and HPLC in 28 days. Thus, based on percentage degradation, C.I. Solvent Red 49 was considered to be not readily biodegradable in nature.
Another supporting experimental study for the structurally similar read across 4-(1-methyl-1-phenylethyl)-N-[4-(1-methyl-1-phenylethyl)phenyl]aniline (CAS: 10081-67-1) from the authoritative database J-CHECK 2017, also suggests that theBiodegradation screening test was conducted for 28 days for evaluating the percentage biodegradability of the test substance.
Concentration of inoculum i.e, sludge is 30 mg/l and initial test substance conc. used in the study is 100 mg/l. The percentage degradation of test substance was found to be 0% by BOD, and 1% by HPLC. Thus, the substance4-(1-methyl-1-phenylethyl)-N-[4-(1-methyl-1-phenylethyl)phenyl]aniline (CAS: 10081 -67 -1)is non-biodegradable in water.
Biodegradation in water and sediment
Estimation Programs Interface (EPI Suite, 2017) prediction model was run to predict the half-life in water and sediment for the test compound5-[[p-(benzylmethylamino)phenyl]azo]-1,4-dimethyl-1H-1,2,4-triazolium chloride(CAS No: 29508 -47 -2). If released in to the environment,7.61% of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of5-[[p-(benzylmethylamino)phenyl]azo]-1,4-dimethyl-1H-1,2,4-triazolium chloride
in water is estimated to be 60 days (1440hrs). The half-life (60 days estimated by EPI suite) indicates that the chemical is persistent in water, whereas the half-life period of5-[[p-(benzylmethylamino)phenyl]azo]-1,4-dimethyl-1H-1,2,4-triazolium chloridein sediment is estimated to be 123.33 days (2960hrs). Based on this half-life value, it indicates that5-[[p-(benzylmethylamino)phenyl]azo]-1,4-dimethyl-1H-1,2,4-triazolium chlorideis persistent in sediment.
Biodegradation in soil
The half-life period of5-[[p-(benzylmethylamino)phenyl]azo]-1,4-dimethyl-1H-1,2,4-triazolium chloride (CAS: 29508-47-2)in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (EPI suite, 2017). If released into the environment,84.3% of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of5-[[p-(benzylmethylamino)phenyl]azo]-1,4-dimethyl-1H-1,2,4-triazolium chloride (CAS: 29508-47-2)in soil is estimated to be120 days (2880hrs). Based on this half-life value of5-[[p-(benzylmethylamino)phenyl]azo]-1,4-dimethyl-1H-1,2,4-triazolium chloride (CAS: 29508-47-2), it is concluded that the chemical is persistent in the soil environment.
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