Registration Dossier
Registration Dossier
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EC number: 214-478-5 | CAS number: 1132-61-2
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- ANALOGUE APPROACH JUSTIFICATION
Please refer to the attached-read across justification in section 13 - Reason / purpose for cross-reference:
- read-across source
- Transformation products:
- not measured
- Key result
- Remarks on result:
- hydrolytically stable based on preliminary test
Reference
Description of key information
The read-across substance was found to be hydrolytically stable (reference 5.1.2-1).
Key value for chemical safety assessment
Additional information
For this endpoint a one-to-one read-across was performed to a chemical similar compound of the same chemical class with a comparable physicochemical profile. The hydrolysis of the source substance as a function of pH was determined in a preliminary test according to OECD Test Guideline 111 under GLP conditions. As no hydrolysis was observed at pH 4, 7 and 9 at 50 °C for 120 h, it was concluded that the substance is hydrolytically stable and the hydrolysis was not investigated further.
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