Registration Dossier
Registration Dossier
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EC number: 269-929-9 | CAS number: 68391-11-7 The complex combination of polyalkylated pyridines derived from coal tar distillation or as high-boiling distillates approximately above 150°C (302°F) from the reaction of ammonia with acetaldehyde, formaldehyde or paraformaldehyde.
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
The toxicokinetic assessment was carried out with 5-ethyl-2-methylpyridine (MEP, CAS no.: 104-90-5, EC no.: 203-250-0). The read-across between the UVCB substance and the model constituent is justified. The toxicokinetic behavior of the substance was assessed to the extent that can be derived from the relevant available information. The main routes of exposure for 5-Ethyl-2-methylpyridine are through inhalation of vapors and skin/eye contact with liquid. Following uptake the parent compound and its metabolites may be distributed throughout the organism. Bioaccumulation is considered not likely. Metabolism may render the substance more polar and most likely less toxic before excretion. Elimination of parent and degradation products is most likely via urine and to a lesser extent via bile and faeces.
Key value for chemical safety assessment
- Bioaccumulation potential:
- no bioaccumulation potential
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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