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EC number: 202-808-0 | CAS number: 99-99-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: original reference not available
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- no data
- GLP compliance:
- not specified
- Melting / freezing pt.:
- 51.9 °C
- Remarks on result:
- other: The atmospheric pressure was not reported.
- Executive summary:
Sax, 1968
The melting point of 4-nitrotoluene is 51.9 °C (the corresponding atmospheric pressure was not reported).
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- no data
- GLP compliance:
- not specified
- Melting / freezing pt.:
- 53 - 54 °C
- Remarks on result:
- other: The atmospheric pressure was not reported.
- Executive summary:
NIOSH (National Institute for Occupational Safety and Health), 2009
The melting point of 4-nitrotoluene is reported to be in the range of 53-54 °C (the corresponding atmospheric pressure was not reported).
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed source, valid collection of data
- GLP compliance:
- not specified
- Melting / freezing pt.:
- 51 °C
- Remarks on result:
- other: The atmospheric pressure was not reported.
- Executive summary:
Hommel, 1997
The melting point of 4-nitrotoluene is 51 °C (atmospheric pressure was not reported).
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- no data
- GLP compliance:
- not specified
- Melting / freezing pt.:
- 51.3 °C
- Remarks on result:
- other: The atmospheric pressure was not reported.
- Executive summary:
MITI, 1992
The melting point of 4-nitrotoluene is 51.3 °C (atmospheric pressure was not reported).
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed surce, valid collection of data
- GLP compliance:
- not specified
- Melting / freezing pt.:
- 51.6 °C
- Remarks on result:
- other: The atmospheric pressure was not reported.
- Executive summary:
Lide, D.R., 2001
The melting point of 4-nitrotoluene is 51.6 °C (atmospheric pressure was not reported).
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed source, valid collection of data
- GLP compliance:
- not specified
- Melting / freezing pt.:
- 55 °C
- Remarks on result:
- other: The atmospheric pressure was not reported.
- Executive summary:
ROEMPP, 2009
The melting point of 4-nitrotoluene is 55°C (atmospheric pressure was not reported).
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed source, valid collection of data
- GLP compliance:
- not specified
- Melting / freezing pt.:
- 53.5 °C
- Remarks on result:
- other: The atmospheric pressure was not reported.
- Executive summary:
Dugal, M. (Kirk-Othmer), 2005
The melting point of 4-nitrotoluene is reported as 53.5 °C (atmospheric pressure was not reported).
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Remarks:
- Adopted according to OECD SIDS (public available peer reviewed source)
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- published data; cited in OECD-SIDS
- GLP compliance:
- not specified
- Melting / freezing pt.:
- 51.3 °C
- Remarks on result:
- other: The atmospheric pressure was not reported.
- Executive summary:
OECD-SIDS, 2003:
The handbook data of Verschueren (Verschueren, K. (1996) Handbook of Environmental Data on Organic Chemicals; 3. ed.) was selected as the key value because the majority of the melting point values are in the range of 51 - 52 °C. Two print publications report 51.3 °C and some other sources very similar values. The latest value, the 2002 data (54 °C) differs from most other values.
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed source, valid collection of data
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): 4-Nitrotoluene
- Analytical purity: not specified - Melting / freezing pt.:
- 44.5 °C
- Remarks on result:
- other: (unstable)
- Melting / freezing pt.:
- 51.9 °C
- Remarks on result:
- other: (stable)
- Executive summary:
Booth, G. (Ullmann's), 2005
4-Nitrotoluene has a melting point of 51.9 °C (stable form). The atmospheric pressure was not reported.
Referenceopen allclose all
The atmospheric pressure was not reported.
Description of key information
The melting point of 4-nitrotoluene was determined in a series of experimental studies to be in the range of 51-55 °C.
The individual study reports (data from handbooks or collection of data) show some deficiencies with respect to the comprehensiveness of the experimental details. Therefore, a reliability of 1 or 2 and thus adequacy as key study was not assignable for any of the individual studies. Consequently, the studies were assigned a Klimisch score of 4 (according to guidance document R.4, ‘not assignable: studies or data […] which are only listed in short abstracts or secondary literature (books, reviews, etc.)). As the individual studies report values are in a similar range, collectively, these studies can be used to conclude on this endpoint and to satisfy the information requirement.
Booth, G. (Ullmann's), 2005
4-Nitrotoluene has a melting point of 51.9 °C (stable form). The atmospheric pressure was not reported.
OECD-SIDS, 2003
The handbook data of Verschueren (Verschueren, K. (1996) Handbook of Environmental Data on Organic Chemicals; 3. ed.) was selected as the key value because the majority of the melting point values are in the range of 51 - 52 °C. Two print publications report 51.3 °C and some other sources very similar values. The latest value, the 2002 data (54 °C) differs from most other values.
Dugal, M. (Kirk-Othmer), 2005
The melting point of 4-nitrotoluene is reported as 53.5 °C (atmospheric pressure was not reported).
ROEMPP, 2009
The melting point of 4-nitrotoluene is 55°C (atmospheric pressure was not reported).
Lide, D.R., 2001
The melting point of 4-nitrotoluene is 51.6 °C (atmospheric pressure was not reported).
MITI, 1992
The melting point of 4-nitrotoluene is 51.3 °C (atmospheric pressure was not reported).
Hommel, 1997
The melting point of 4-nitrotoluene is 51 °C (atmospheric pressure was not reported).
NIOSH (National Institute for Occupational Safety and Health), 2009
The melting point of 4-nitrotoluene is reported to be in the range of 53-54 °C (the corresponding atmospheric pressure was not reported).
Sax, 1968
The melting point of 4-nitrotoluene is 51.9 °C (the corresponding atmospheric pressure was not reported).
The value reported in Ullmann's handbook (51.9 °C, stable form) was chosen as key value for chemical safety assessment, as stable and unstable form were distinguished.
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- 51.9 °C
Additional information
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