Registration Dossier
Registration Dossier
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EC number: 206-839-0 | CAS number: 381-73-7
Endpoint summary
Administrative data
Description of key information
Corrosive effect observed in skin an eyes
Key value for chemical safety assessment
Skin irritation / corrosion
Link to relevant study records
- Endpoint:
- skin irritation: in vivo
- Data waiving:
- other justification
- Justification for data waiving:
- other:
Reference
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (corrosive)
Eye irritation
Link to relevant study records
- Endpoint:
- eye irritation: in vivo
- Data waiving:
- other justification
- Justification for data waiving:
- the study need not be conducted because the substance is a strong acid (pH <= 2.0) or base (pH => 11.5)
Reference
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Skin irritation/corrosion:
As per the Annex VII column 2 of REACH regulation, the available information indicates that the substance difluoroacetic acid is a strong acid (pH ≤ 2.0). Also the substance is classified as very toxic in contact with skin. Thus testing for skin irritation is not likely. Hence this endpoint was considered for waiver
Eye irritation:
As per the Annex VII column 2 of REACH regulation, the available information indicates that the substance difluoroacetic acid is a strong acid (pH ≤ 2.0).Alsosubstance is classify as corrosive to the skin or irritating to eyes. Thus testing for eye irritation is not likely. Hence this endpoint was considered for waiver
Justification for selection of skin irritation / corrosion endpoint:
As per the Annex VII column 2 of REACH regulation, the available information indicates that the substance difluoroacetic acid is a strong acid (pH ≤ 2.0). Also the substance is classified as very toxic in contact with skin. Thus testing for skin irritation is not likely. Hence this endpoint was considered for waiver
Justification for selection of eye irritation endpoint:
As per the Annex VII column 2 of REACH regulation, the available information indicates that the substance difluoroacetic acid is a strong acid (pH ≤ 2.0). Also substance is classify as corrosive to the skin or irritating to eyes. Thus testing for eye irritation is not likely. Hence this endpoint was considered for waiver
Effects on skin irritation/corrosion: corrosive
Effects on eye irritation: corrosive
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
