Registration Dossier
Registration Dossier
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EC number: 206-839-0 | CAS number: 381-73-7
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The lethal concentration (LC50) value of difluoroacetic acid in aquatic invertebrate (Daphnia magna) in a 48 hr study on the basis of mortality effect was found to be 235.793 mg/L. Based on this prediction it can be infered that the target chemical is non toxic to aquatic environment.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 235.793 mg/L
Additional information
No. of studies reviewed for short – term toxicity to fish from reliable sources having Klimisch rating 2 and 4.
The summary of the results are presented below
Sr. No. |
Endpoint |
Effect values |
Basis for effects |
Duration |
Species |
Sources |
1 |
LC50 |
235.79 mg/L |
Mortality |
48 hrs |
Daphnia magna |
Predicted data from QSAR |
2 |
LC50 |
21767.93 mg/L |
Mortality |
48 hrs |
Daphnia magna |
Predicted data from ECOSAR |
By applying weight of evidence approach to the test substance difluoroacetic acid, the endpoint value was found to LC50 = 235.79 mg/L & 21767.93 mg/L in a 48 hrs. to 48 hrs. study on the basis of mortality effect. The BCF value of difluoroacetic acid reported was not >= 500 as well as the substance was found to be rapidly degradable
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