Registration Dossier
Registration Dossier
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EC number: 219-775-3 | CAS number: 2528-61-2
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Based on the available datafrom the read-across approach, it can be concluded, that heptanoyl chloride as well as its structurally similar substance are with high probability acutely not harmful toaquatic invertebrates.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Dose descriptor:
- EC50
- Effect concentration:
- 202.9 mg/L
Additional information
The assessment of the acute toxicity of the heptanoyl chloride to aquatic invertebratesis is based on a read-across to the structurally related substance pivavoyl chloride.
Pivavoyl chloride rapidly hydrolyses in contact with water and forms pivalic acid (CAS 75-98-9) and HCl (CAS 7647-01-0). Therefore, the acute toxicity to aquatic invertebrates will be assessed based on the information available for the hydrolysis products pivalic acid and HCl.
The reliable experimental data are available for the hydrolysis product of the source substance: pivalic acid. The acute toxicity of the hydrolysis product pivalic acid to aquatic invertebrates was tested according to US EPA – 660/3-75-009 (Methods for Acute Toxicity with fish and Macroinvertebrates, and Amphibians; 1975) using Daphnia magna as test organism (EG & G Bionomics, 1977). The 48-h EC50 was found to be 202.9 mg/L, based on nominal test concentrations.The test concentrations were not analytically monitored.
Based on the available data from the read-across approach, it can be concluded, that heptanoyl chloride as well as its structurally similar substance are with high probability acutely not harmful toaquatic invertebrates.
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