Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 273-054-8 | CAS number: 68937-17-7
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Dimethylsilanediol:
A 72-hour EC50 of >118 mg/l and a NOEC of ≥118 mg/l have been determined for the effects of dimethylsilanediol on growth rate of Pseudokirchnerella subcapitata.
Methylsilanetriol:
A 72 h EC50 value of >120 mg/l and NOEC of ≥120 mg/l (nominal concentrations) have been determined for the effects of a read-across substance, trimethoxy(methyl)silane, on growth rate of Pseudokirchnerella subcapitata. The same results expressed in terms of geometric mean measured concentrations of the test substance, trimethoxy(methyl)silane, were >3.6 mg/l and ≥3.6 mg/l, respectively. It is likely that the difference between the nominal and measured concentrations is a result of the rapid hydrolysis of the substance and that the test organisms were predominantly exposed to the hydrolysis products of the substance. The nominal concentrations are used for PNEC derivation because the substance hydrolyses rapidly and so it is appropriate to consider the effects of the hydrolysis products rather than the parent substance.
Key value for chemical safety assessment
Additional information
No test data for short-term toxicity to fish are available fordisilane, chloro Me derivs. Disilane, chloro Me derivs.is expected to hydrolyse rapidly in contact with water to give hydrogen chloride and, initially,the silanol derivatives of the three main constituents, and further hydrolyse to methylsilanetriol and dimethylsilanediol.
Effects of hydrogen chloride on aquatic organisms are limited to those that result from changes to pH in unbuffered media.
Short-term toxicity to fish data are available for dimethylsilanediol. For methylsilanetriol,data have been read-across fromthe related substance trimethoxy(methyl)silane. Under conditions relevant to ecotoxicity assessment this will hydrolyse to methylsilanetriol in the course of the tests. The other hydrolysis product, methanol, is non-toxic to the environment and it is considered unlikely that its presence significantly affected the results of the test performed with trimethoxy(methyl)silane.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
