Registration Dossier
Registration Dossier
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EC number: 608-035-9 | CAS number: 27014-42-2
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1996-11-18 - 1996-11-22
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study without deviations. non-GLP
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 997
- Report date:
- 1997
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Deviations:
- no
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Poly(oxy-1,2-ethanediyl), a,a',a'',a'''-[1,2-ethanediylbis(nitrilodi-2,1-ethanediyl)]tetrakis[w-hydroxy-
- EC Number:
- 608-035-9
- Cas Number:
- 27014-42-2
- IUPAC Name:
- Poly(oxy-1,2-ethanediyl), a,a',a'',a'''-[1,2-ethanediylbis(nitrilodi-2,1-ethanediyl)]tetrakis[w-hydroxy-
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test organisms
- Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
- Details on test organisms:
- Breeding by HOECHST AG, Hoechst Marion Roussel, Drug Safety
The fish had a mean body length of 3.1 cm (2.7 - 3.3 cm/ s = ± 0.22)
Study design
- Test type:
- not specified
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
Test conditions
- Test temperature:
- 21.3 - 21.5 (°C)
- pH:
- 7.6-8.1
- Dissolved oxygen:
- 6.3-10.0 mg/l
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 10 000 mg/L
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- The fish of 10,000 mg / L group showed symptoms during the entire experimental period but showed no lethality.
In the control group (0 mg/l) also no lethality appeared.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The LC 50 after 96 hours is >10000 mg / L.
- Executive summary:
The LC 50 after 96 hours is >10000 mg / L.
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