(2S)-3-Methyl-2-[N-({2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1-biphenyl]-4-yl}methyl)pentanamido]alkanoic acid

Additional physico-chemical information

Administrative data

Endpoint:

other: self-reactive

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2012

Report date:

2012

Materials and methods

Principles of method if other than guideline:

The SADT of test substance was determined by using methodology H.4 (using Dewar flasks) in accordance with the Recommendations on the Transport of Dangerous Goods.

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

N-Pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine

EC Number:

604-045-2

Cas Number:

137862-53-4

Molecular formula:

C24 H29 N5 O3

IUPAC Name:

N-Pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine

Results and discussion

Results:

The test substance has not to be classified in the Division 4.1 - self-reactive substances.
SADT50L > 75 °C

Any other information on results incl. tables

Volume of the Dewar flask [mL]	Cooling time[hours]	Heat losses [mW·kg^-1·K^-1]	Dewar used at a temperature of [°C]
500	16	50	75

 

The heat loss determined is in the range for solids indicated in the Recommendations on the Transport of Dangerous Goods for a drum of 50 L.

The maximal temperature rise in the centre of the sample after reaching the oven-temperature is below 1 K thus not reaching the test criterion value of 6 K.