Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Short-term aquatic invertebrates: OECD 202; Daphnia magna 48h EC50 was 66.2 mg a.i./L.

Freshwater Algae: OECD 201; Raphidocelis subcapitata 72h EC50 and EC10 values for growth rate were determined to be 53 and 18 mg/L, respectively. The 72h NOEC was 11 mg/L.

Additional information

Two aquatic toxicity studies are available for substance BTFB: a 72-h growth inhibition study with freshwater alga Raphidocelis subcapitata and a 48-h immobility study with Daphnia magna. Due to the test substance volatility in both tests, rigorous precautions were taken to minimize losses through evaporation.  Both studies were conducted under closed-system conditions with minimized headspace. Additionally, special precautions were taken during collection and analysis of samples to avoid losses through volatilization.  Despite the special handling and precautions, the measured concentrations resulted in concentrations well below the nominal concentrations. The severe effect of volatilization was especially noted during the analytical treatment of D. magna samples where the analytical concentrations were only 3.2 to 13% of the nominal concentrations, therefore nominal concentrations are more representative of exposure to the test system. Based on the rapid volatilization of BTFB from aqueous media, BTFB is not expected to produce adverse effects in aquatic species.


Based on its aquatic toxicity and lack of biodegradability, BTFB is classified as Aquatic Chronic 3.