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Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

comparable to guideline study with acceptable restrictions

Reason / purpose for cross-reference:

reference to same study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

GLP compliance:

no

Type of method:

flask method

Water solubility:

< 0.4 mg/L

Conc. based on:

test mat. (dissolved fraction)

Temp.:

20 °C

Remarks on result:

other: pH specified in 'any other info on results incl. tables' below

Results

Agitation period	Sample	pH	Concentration of test item in test solution
2 days	1a	7.0	< 0.40 mg/L
	1b	7.0
3 days	2a	7.0
	2b	7.2

 

 

Discussion

The test item was hardly solubleinwater and the water solubility was less than the concentration calculated from the limit of quantification. Then, the analytical method was judged to be valid because the acceptable recovery rate (average of recovery rates : 97.2%) was obtainedinthe recovery test.

Therefore, it was concluded that the test results were acceptable.

Description of key information

< 0.40 mg/L at 20 °C and pH 7.0 -7.2 (flask method, OECD 105)

Additional information

The water solubility of the test item was below the limit of quantification.