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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

The 48-hour EC50 value was determined by empirical estimation to be >97 mg a.i./L. Additional testing to further define the EC50 value was not conducted as this would exceed OECD guideline (100mg/L). The No-Observed-Effect Concentration (NOEC) was determined to be 97 mg/L. The highest concentration producing 0% immobilization was 97 mg/L. The lowest concentration producing 100% immobilization was > 97 mg/L.

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
97 mg/L

Additional information

In a GLP compliant guideline, the effect of the test substance on Daphnia magna was determined. As no concentration tested resulted in a ≥50% immobilization, the 48-hour EC50 value was empirically estimated to be > 97 mg/L, the highest mean measured concentration tested. Additional testing to further define the EC50 value was not conducted since the highest nominal treatment level tested (100 mg/L) is the highest concentration required by the OECD guideline.

 

The No-Observed-Effect Concentration (NOEC) was determined to be 97 mg/L. The limits of test substance concentration producing 0% and 100% immobilisation are indicated. The highest concentration producing 0% immobilization was 97 mg/L. The lowest concentration producing 100% immobilization was > 97 mg/L.