Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 639-656-3 | CAS number: 8016-26-0
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vitro / ex vivo
- Type of information:
- not specified
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Cross-reference
- Reason / purpose for cross-reference:
- read-across source
Reference
- Endpoint conclusion:
- no adverse effect observed (not irritating)
- Endpoint conclusion:
- no adverse effect observed (not irritating)
- Endpoint conclusion:
- no study available
PAGmay cause mild skin irritation
Sobre la base de la información disponible, la ECHA resultó ser moderadamente irritante tanto para los ojos como para los modelos de piel y animal. No hay datos vacíos para la irritación / corrosión del punto final. No hay información disponible para este punto final. Sin embargo, no hay razón para creer que estos resultados no son aplicables a los seres humanos
Pictogramas:
Data source
Reference
- Reference Type:
- publication
- Title:
- Eye irritation
- Author:
- Ref 5.3.2.1
- Year:
- 1 995
- Bibliographic source:
- Eye irritation
- Report date:
- 1995
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 405 (Acute Eye Irritation / Corrosion)
- Deviations:
- not specified
- GLP compliance:
- yes
Test material
- Reference substance name:
- 958872-63-4
- Cas Number:
- 958872-63-4
- IUPAC Name:
- 958872-63-4
Constituent 1
Results and discussion
In vitro
Results
- Irritation parameter:
- in vitro irritation score
- Run / experiment:
- Ejecución 1 (duración de la exposición: 10 min.)
- Value:
- > 0.1 - < 1
- Vehicle controls validity:
- not specified
- Negative controls validity:
- not specified
- Positive controls validity:
- not specified
- Remarks on result:
- not measured/tested
In vivo
Results
- Irritation parameter:
- conjunctivae score
- Basis:
- animal #2
- Time point:
- 24 h
- Remarks on result:
- probability of weak irritation
Applicant's summary and conclusion
- Interpretation of results:
- study cannot be used for classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
