Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
in vivo mammalian somatic cell study: cytogenicity / erythrocyte micronucleus
Type of information:
other: read across based on OECD Toolbox v3.4
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
see attached OECD Toolbox study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guideline
Guideline:
OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)
GLP compliance:
not specified
Type of assay:
other: genetic toxicity in vivo

Test material

Constituent 1
Chemical structure
Reference substance name:
N-(methoxymethyl)acrylamide
EC Number:
222-871-8
EC Name:
N-(methoxymethyl)acrylamide
Cas Number:
3644-11-9
Molecular formula:
C5H9NO2
IUPAC Name:
N-(methoxymethyl)prop-2-enamide

Test animals

Species:
mouse
Strain:
not specified

Results and discussion

Test results
Key result
Sex:
male/female
Genotoxicity:
negative
Toxicity:
not specified

Applicant's summary and conclusion