Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Skin irritation / corrosion

Currently viewing:

Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
other: read across based on OECD Toolbox v3.4
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
see attached OECD Toolbox study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guideline
Guideline:
other: read across
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
N-(methoxymethyl)acrylamide
EC Number:
222-871-8
EC Name:
N-(methoxymethyl)acrylamide
Cas Number:
3644-11-9
Molecular formula:
C5H9NO2
IUPAC Name:
N-(methoxymethyl)prop-2-enamide

Test animals

Species:
rabbit
Strain:
not specified

Results and discussion

In vivo

Results
Irritation parameter:
other: no data
Basis:
mean
Score:
0
Max. score:
8
Reversibility:
fully reversible
Remarks on result:
other: not irritating

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met