2,3,4-trihydroxybenzophenone

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2015-07-02 to 2015-07-20

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

reference to same study

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Version / remarks:

2008

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Deviations:

no

GLP compliance:

no

Type of method:

differential scanning calorimetry

Remarks:

A measurement with the capillary method was additionally performed to clarify the results of DSC measurements.

Key result

Boiling pt.:

>= 350 °C

Decomposition:

yes

Decomp. temp.:

>= 350 °C

Remarks on result:

other:

Remarks:

Atmospheric pressure not specified, normal pressure is presumed

Results
DSC measurement
Two DSC measurements showed an endothermal effect after the melting in the temperature range of 350 to 410 °C. No further endothermic nor exothermic effects were seen up to the final test temperature of 500 °C. The mass loss after the DSC measurements was ca. 83 %.

 

Table 1 – DSC measurement results

Test item [mg]	Starting test temperature [°C]	Final test temperature [°C]	Temperature range (boiling) [°C]	Onset [°C]	Observations
7.35	25	500	350 – 410	Multi-stage	Black residue seen after the measurement
8.57

 

A measurement with the capillary method was performed to clarify the results of the DSC measurements. Since this measurement was performed only as a verifying screening a high heating rate of 10 K/min was chosen and therefore the absolute temperature values derived with the capillary method are not as accurate as the DSC results. The filling height of the test item was approximately 5 mm.

 

Table 2 – Capillary method results

Set point [°C]	End point [°C]	Remarks
300	410	During the experiment the test item discoloured from amber to black Ca. 385 °C: continues boiling Ca. 405 °C: black residue in tube

 

Based on both methods executed, it was concluded that the test item boiled under decomposition starting at ca. 350 °C.

Conclusions:

DSC measurements and the capillary method showed that the test item boiled under decomposition starting at approximately 350 °C.

Executive summary:

A study was conducted according to OECD test guideline 103 and Regulation (EC) No 440/2008 method A.2. The boiling point was determined by differential scanning calorimetry (DSC 25 - 500 °C). The test item and the reference were heated up from the starting temperature to the final temperature at a constant heating rate of 10 K/min in a defined atmosphere (nitrogen). Open crucibles were used as containers for the test item and as empty reference crucible. The quantity of heat absorbed or released was measured and recorded. In addition, measurement with the capillary method with a heating rate of 10 K/min was performed to clarify the results of the DSC measurements. The filling height of the test item was approximately 5 mm. Under consideration of the results from the DSC measurements and the capillary method it was concluded that the test item boiled under decomposition starting at approximately 350 °C.

Description of key information

DSC measurements and the capillary method showed that the test item boiled under decomposition starting at approximately 350 °C.

Key value for chemical safety assessment

Boiling point at 101 325 Pa:

350 °C

Temperature of decomposition (state purity):

350 °C

Additional information

A study was conducted according to OECD test guideline 103 and Regulation (EC) No 440/2008 method A.2. The boiling point was determined by differential scanning calorimetry (DSC 25 - 500 °C). The test item and the reference were heated up from the starting temperature to the final temperature at a constant heating rate of 10 K/min in a defined atmosphere (nitrogen). Open crucibles were used as containers for the test item and as empty reference crucible. The quantity of heat absorbed or released was measured and recorded. In addition, measurement with the capillary method with a heating rate of 10 K/min was performed to clarify the results of the DSC measurements. The filling height of the test item was approximately 5 mm. Under consideration of the results from the DSC measurements and the capillary method it was concluded that the test item boiled under decomposition starting at approximately 350 °C.