Registration Dossier
Registration Dossier
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EC number: 429-080-9 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 16th June 1999 - 1st Feb 2000
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 000
- Report date:
- 2000
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.2 (Acute Toxicity for Daphnia)
- GLP compliance:
- yes
Test material
- Reference substance name:
- -
- EC Number:
- 429-080-9
- EC Name:
- -
- Cas Number:
- 198904-85-7
- Molecular formula:
- C17 H21 N3 O2
- IUPAC Name:
- Tert-butyl 2-[4-(2-pyridinyl) phenylmethyl] hydrazine carboxylate
- Test material form:
- solid: bulk
Constituent 1
- Specific details on test material used for the study:
- Identity of test material same as for substance defined in section 1
Test solutions
- Vehicle:
- no
- Details on test solutions:
- Identity and concentration of auxiliary solvent for dispersal: No auxiliary solvent was required
Test organisms
- Test organisms (species):
- Daphnia magna
Test conditions
- Hardness:
- ca. 88 mg CaCO3/L
Results and discussion
Effect concentrationsopen allclose all
- Key result
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- 100 mg/L
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 30.34 mg/L
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC100
- Effect conc.:
- 50 mg/L
- Key result
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 12.5 mg/L
- Details on results:
- %Concentration loss over test: 3 ... 10
Applicant's summary and conclusion
- Conclusions:
- The 24hr EC50 value was calculated to be 100mg/l
The 48hr EC50 value was calculated to be 30.34 mg/l
The lowest concentration causing 100% immobility was 50mg/l and the highest concentration causing no immobility was 12.5mg/l. However, one immobile daphnia magna was observed at the lowest test concentration of 6.3 mg/l
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